MAPT and dementia: A total of 1,645 participants were included, among which 1032 visually read as Tau-PET-negative (n = 628 cognitively unimpaired, n = 259 MCI, and n = 145 dementia) and 613 visually read as Tau-PET-positive (n = 60 cognitively unimpaired, n = 154 MCI, and n = 399 dementia).