In plasma of 10-week-old C57BL/6J Apoe−/− mice receiving angiotensin II infusion for 4 weeks, aneurysms were developed and miR-15a levels were confirmed to be significantly up-regulated, although no difference could be observed between the mice with ruptured vs. non-ruptured aneurysms (Fig. 1D). Here, AGT is linked to aneurysm.