INS and type 1 diabetes mellitus: People with T1DM may be on different regimens; whilst in parts of the world where technology is available, the use of insulin pumps is very common (see next section), many people are on a basal-bolus regimen, that is, a dose of ultrarapid- or rapid-acting insulin at the time of a meal, with a longer-acting, basal insulin being given once or twice daily.