In addition to factors described earlier, the overlap of FMRP N-tat associated proteins observed in tsA-201 FMR1 KO cells and FXS patient-derived neurons, pointed to C1QBP, TRIM28, STAU1, and VDAC2 as factors supporting functional rescue, all of which have previously been identified to interact with FMRP or have a role in FXS (37, 63). Here, VDAC2 is linked to fragile X syndrome.