The expression of TGF‐β1 in macrophages has a critical role in the pathogenesis of liver fibrosis.[24] Indeed, scRNAseq analysis of liver NPCs (GSE145086) showed that there is a TGF‐β1‐mediated connection between macrophages and HSCs in CCl4‐induced liver fibrosis (Figure4A,B; Table S1, Supporting Information).[27] In CCl4‐induced liver fibrosis, TGF‐β1 expression in liver macrophages was significantly elevated compared to that of controls (Figure 4C,D). This evidence concerns the gene TGFB1 and Hepatic fibrosis.