Infiltrated monocytes in the liver are further differentiated into inflammatory, scar‐associated macrophages that serve as the major modulators of the fibrogenic process in chronic liver injury.[10] These macrophages release fibrogenic factors, including transforming growth factor (TGF)‐β and platelet‐derived growth factor, which stimulate the transformation of quiescent HSCs into an activated form producing ECM, thus ultimately promoting liver fibrosis. This evidence concerns the gene TGFB1 and Hepatic fibrosis.