Based on the two most recent PD GWAS [28, 30], other PD risk loci with a possible effect on immunological functions include FCGR2A, RAB29, MAP4K4, BST1, TRIM40, FAM49B, CUEDC2, IGSF9B, CD19/NFATC2IP, CYLD, SPPL2B, JAK1 and HS1BP3 (and there may be many more). This evidence concerns the gene SPPL2B and Parkinson disease.