GSVA scores of CEDGs were positively correlated with infiltration score and cell types of NK, NKT, monocyte, cytotoxic, Th2, macrophage, exhausted, CD8_T, effector_memory, gamma_delta and Th1, while negatively related to cell types of central_memory, th17, iTreg, CD4_naive, CD8_naive, Bcell and Tr1 in most cancers (S13A Fig). The gene discussed is CD8A; the disease is cancer.