Using an AML model (48), we i.v. injected NOD-scid IL-2Rγnull (NSG) mice with firefly luciferase–labeled (FFLuc-labeled) CD155+ or CD155-KO AML cells, followed by an infusion of either PBS, mock T cells, or CD155 CAR-T cells (Figure 3A). This evidence concerns the gene PVR and acute myeloid leukemia.