Interestingly, in KEGG pathway enrichment, the target genes related to miRNA sepsis biomarkers were enriched in pathways in cancer (including ErbB and p53 signaling pathways) and pathways in actin cytoskeleton regulation, while protein sepsis biomarkers were mapped in infectious disease, autoimmune disease pathways, and inflammation processes. The gene discussed is TP53; the disease is autoimmune disease.