However, the large cohorts available did not invesitgate the diagnosed cases adequately; leaving any mucin-producing malignancy possible MECs although >50% of salivary gland tumors secret mucin luminally or extra-luminally. This study examined the expression of stem cell markers Nanog, SOX2, OCT4, and MENA in salivary MEC using immunohistochemistry and to confer, whether or not, they may have a potential role in defining the tumoral molecular profile. The gene discussed is POU5F1; the disease is tumor of salivary gland.