As shown in Fig. 5, the common targets have implicated in atherosclerosis possibly through related pathways including HIF-1 signaling pathway (hsa04066), regulation of actin cytoskeleton (hsa04810), calcium signaling pathway (hsa04020), macrophage stimulating protein MSP signaling network map (WP5353), AGE/RAGE pathway (WP2324), interleukin-4 and interleukin-13 signaling (rhsa6785807), signaling by receptor tyrosine kinases (rhsa9006934), adaptive immune system (rhsa1280218), hemostasis (rhsa109582). This evidence concerns the gene IL4 and atherosclerosis.