MIB2 and paroxysmal nocturnal hemoglobinuria: Our findings revealed a significant up‐regulation in MIB2 protein level in both the whole‐cell lysate (1.26 ± 0.30 vs. 0.68 ± 0.27, p < 0.0001) and nuclear protein lysate (2.45 ± 0.52 vs. 0.23 ± 0.08, p < 0.0001) in PNH patients, particularly in the nuclear fraction (Figure 6A,B).