Interestingly, while BDNF, which increases tubulin tyrosination [92], H3‐Ser‐ADPR and TyrRS in neurons [11] protects against heart failure [174], trans‐RSV, which decreases tubulin tyrosination, H3‐Ser‐ADPR and TyrRS, increases the risk of CVDs [175]. The gene discussed is BDNF; the disease is heart failure.