Pathogen invasion is usually recognized by pathogen recognition receptors (PRR) such as the peptidoglycan recognition proteins (PGRPs), Gram‐negative binding proteins (GNBPs), and β‐glucan recognition proteins (βGRPs) for bacterial and the serine protease Persephone (Psh) for fungal infections. The gene discussed is PGLYRP1; the disease is fungal infectious disease.