ADM and stroke disorder: Pro-adrenomedullin (pro-ADM), a precursor of adrenomedullin (ADM), has been identified as a potential biomarker in various acute conditions such as sepsis, acute heart failure, cardiac arrest, and stroke (Liang et al., 2023; Hagag et al., 2011; Spoto et al., 2023; Zelniker et al., 2023; Ishiyama et al., 2023).