By incubating three distinct tumor cells lines that constitutively express no, low, and high MHC I levels (NCCIT, SKBR-3, and PC3, respectively) with platelets, Placke et al27 demonstrated that tumor cells incubated with platelets showed expression of CD61 (a platelet marker) and high-levels of platelet-derived MHC-I on their plasma membrane. This evidence concerns the gene ITGB3 and neoplasm.