TWIST1 and gastric cancer: We refined these findings by performing a correlation meta-analysis and predicting transcription factor-binding sites, allowing us to prioritize six putative transcriptional regulators of THY1. Finally, we validated these regulatory interactions by combining conservation analyses with chromatin immunoprecipitation (ChIP) assays, providing experimental evidence supporting the role of TWIST1 and SNAI2 as potential key regulators of THY1 expression in gastric cancer cells.