Overall, these results suggest that TWIST1 and SNAI2 likely play prominent roles in the regulation of THY1 expression in the studied gastric cancer cell lines, with specific binding sites (I2, P1, P2, and P3 for TWIST1 and P1, P2, and P3 for SNAI2) in the THY1 regulatory regions contributing to its differential expression. This evidence concerns the gene SNAI2 and gastric cancer.