However, it is noteworthy that during the course of sepsis, neutrophils can also mitigate oxidative stress and endothelial dysfunction by releasing extracellular vesicles carrying superoxide dismutase 2 (SOD2), thus alleviating symptoms of disseminated intravascular coagulation (DIC) (Bao et al., 2022). The gene discussed is SOD2; the disease is Disseminated intravascular coagulation.