Additional findings are displayed in net league tables, forest plots, and funnel plot.<h4>Conclusions</h4>A daily dose of 100 ml of XBJ was associated with improvement in APTT and CRP levels in patients with sepsis, a daily dose of 150 ml may decrease 28-day mortality; while XBJ with a single-day dose of 300 ml is more effective at improving the APACHE II score, higher dosages correlated with improved prognosis in these patients compared to other doses. This evidence concerns the gene CRP and Sepsis.