After adjusting for age, comorbidity and SARS-CoV-2 variant, the hazard of Long COVID was 1.58 up to 4.12-fold in COVID-19 patients with upregulated baseline protein levels of SLAMF1, TNF, TSLP, IL15RA, IL18, ADA, CXCL10, IL17C, NT3, and CXCL9 (Figure 4E). This evidence concerns the gene TNF and COVID-19.