In addition, we validated this finding using two external online tools, LOGpc (https://bioinfo.henu.edu.cn/index.html) and KM-Plotter (https://kmplot.com/analysis/), both of which consistently demonstrated that high ALG3 expression was associated with significantly worse overall survival in HCC patients (Supplementary Figure S1). This evidence concerns the gene ALG3 and hepatocellular carcinoma.