SRF3-mediated enhancement of miRNA-17/20 processingalters expression of their target mRNAs encoding key cell cycle inhibitorcyclin-dependent kinase inhibitor 1A (CDKN1A/p21), which leads to enhance cell cycle progression and proliferation inmouse pluripotent cells, human cancer cell lines and primary colorectal tumors[44]. This evidence concerns the gene CDKN1A and colorectal neoplasm.