Similarly, among the members of miRNA-17-92cluster, miRNA-18a, miRNA-19a and miRNA-19b, were significantly reduced in thecardiac biopsies of idiopathic cardiomyopathy (ICM) patients in old age with HF,with concurrent induction of the transcript levels of CTGF and TSP-1 [69]. Here, THBS1 is linked to hydrops fetalis.