The miRNA-92a promotesWNT/β-catenin signaling activity by directly targeting KLF4,GSK3β, and Dickkopf-3 (DKK3), which subsequently enhances chemoresistanceof colorectal cancer cells as well as stem cell-like phenotypes to inducecolorectal cancer cell progression [190]. This evidence concerns the gene DKK3 and colorectal cancer.