Additionally, inflammation is central to the development of NAFLD, andthis systemic inflammation also influences cardiac remodelling through increasedproduction of proinflammatory cytokines like TNF-α and interleukin-6(IL-6), which impair myocardial function, induce reactive oxygen species (ROS)overproduction, and increase myocardial fibrosis. Here, IL6 is linked to metabolic dysfunction-associated steatotic liver disease.