The median ALT levels were 48 U/L in the HFS group compared to 28 U/L in the HFS-f2ree group (P<0.001), the median AST levels were 38 U/L versus 26 U/L (P<0.001), and the median GGT levels were 17 U/L versus 15 U/L (P=0.001). Here, GPT is linked to Hand-foot syndrome.