Traditional treatments for diabetes include lifestyle modifications (Schellenberg et al., 2013; Li et al., 2003), oral hypoglycemic agents (such as metformin, α-glucosidase inhibitors, and insulin sensitizers) (Tran et al., 2015a), and injectable medications (such as insulin and glucagon-like peptide-1) (Tran et al., 2015b). This evidence concerns the gene INS and diabetes mellitus.