While clinical trials are scarce (Klausen et al., 2022; Hendershot et al., 2025), recent findings from Hendershot et al., support the observation from several retrospective and prospective studies that GLP-1 RAs have the potential to aid in the treatment of alcohol use disorder (AUD) (reviewed in Subhani et al., 2024). The gene discussed is GCG; the disease is alcohol abuse.