CCR7 and multiminicore myopathy: To further investigate T-cell activation and differentiation states in MMD, we assessed the expression of several established markers: CD45RO (memory T cells) [37], CCR7 (T-cell chemotaxis) [38], CD25 (activated T cells/Tregs) [39], CD69 (early activation) [40], CD127 (mature T cells, particularly Tcm cells) [41], and HLA-DR (antigen presentation/activation) [42].