When evaluating these tumor markers as continuous variables, we observed no difference in IFNγ expression (P = 0.87) or log10 TMB (P = 0.87); however, we have noted a slightly elevated CD8+ infiltration in HG-T compared to the other MT-HGs (P = 0.09; Extended Data Fig. 3b–d). Here, CD8A is linked to neoplasm.