RSAD2 and postpartum depression: Nevertheless, findings in our study are in line with those of Rudzinskas et al. and others, pointing to differences among a broad range of immune-relevant genes differentially regulated in women with PPD/depressive symptoms, an overall down regulation of genes in PPD, and the identification of the DEG, RSAD2 (Fig. 7), which is involved in immune signalling,  and has been shown to be altered in PPD lymphoblastoid cell lines [21] and postpartum depression [20].