PLK1 and Duchenne muscular dystrophy: To identify biological processes related to these overlapping genes, we performed gene annotation enrichment analysis, which revealed pathways and processes including “extracellular matrix organization” (Adamts2/4/7/14, Col1a1/2, Col5a2, Fn1, Has2, Mmp15, Tgfb1), “cytoskeleton in muscle cells” (Acta1, Myh1/3, Myl1, Tnni1, Tnnt2, Tpm2, Ttn), “muscle structure development” (Cav3, Cdk1, Id3, Myog, Sdc1), and “mitotic cell cycle” (Ccnb1/2, Cdca8, Cdc45, Cenpa, Cenpf, Cenpm, Kif4/11/15/20a/22/23, Plk1/2) as the top enriched terms in satellite cells from both DMD models (Fig. 3F).