Increased TSB predominantly results from increased bilirubin production from increased red blood cell turnover from conditions such as glucose-6-phosphate dehydrogenase (G6PD) deficiency, ABO and Rhesus blood group incompatibility, cephalohaematoma, subgaleal haemorrhage, intracranial haemorrhage, polycythaemia and sepsis [5–8]. This evidence concerns the gene G6PD and hyperinsulinemic hypoglycemia, familial, 4.