Second, cis-MRBEE identified CR1 expression in the basal ganglia, hippocampus, and oligodendrocytes as potentially causal for Alzheimer’s disease (AD), amyloid-beta-42 levels (A\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{upgreek}\usepackage{mathrsfs}\setlength{\oddsidemargin}{-69pt}\begin{document}$\beta $\end{document}42), and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF), utilizing both expression QTLs (eQTLs) and single-cell eQTLs (sceQTLs) as instruments. The gene discussed is MAPT; the disease is Alzheimer disease.