These data indicate that the GP63 protein derived from stationary-phase promastigotes/amastigotes of Leishmania infantum, a causative agent of visceral leishmaniasis, exhibits a higher degree of sequence conservation compared to the corresponding GP63 proteins from L. tropica and L. major, which are associated with cutaneous leishmaniasis. The gene discussed is LMLN; the disease is cutaneous leishmaniasis.