Comparison of the baseline data of these patients revealed significant differences in age, height, weight, SBP, DBP, WBC, RBC, Hb, BUN, CR, Alb, HDL, LDL, history of hypertension and NAFLD, DPN, DPV, DR, CHD, eGFR and UACR between DN and T2DM groups (P < 0.05) (Fig. 1; Table 1). This evidence concerns the gene GSTM1 and metabolic dysfunction-associated steatotic liver disease.