However, there were six biomarkers that differed between HC and T1D patients based on un-corrected p-values; Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 5 (ENPP5) was lower in T1D than HC group while Complement C1q Subcomponent Subunit A (C1QA), Iduronate 2-Sulfatase (IDS), Niacilin (NCLN), Sialic Acid-binding Ig-like Lectin 10 (SIGLEC10) and Trefoil Factor 2 (TFF2) were higher in T1D than HC group (Fig. 2). The gene discussed is ENPP5; the disease is type 1 diabetes mellitus.