BIRC5 and neoplasm: BIRC5 has been identified as a significant contributor to tumor progression and development, chemoresistance, and metastasis through its participation in several signaling pathways, such as the JAK/STAT, Notch, PI3 K/AKT, TGF‐β, NF‐κ, Wnt/β‐catenin, Hippo pathways and p38/MAPK (Martínez-García et al. 2019).