For instance, the lncRNA Neat1 has been shown to promote glycolysis in BC cells by binding to and forming a scaffold for the assembly of PGK1/PGAM1/ENO1 complexes.[20] However, the vast majority of lncRNAs remain uncharacterized in the context of BC metabolic reprogramming, and the specific mechanisms through which they exert their effects are still poorly defined. This evidence concerns the gene ENO1 and breast cancer.