PGAM1 and breast cancer: For instance, the lncRNA Neat1 has been shown to promote glycolysis in BC cells by binding to and forming a scaffold for the assembly of PGK1/PGAM1/ENO1 complexes.[20] However, the vast majority of lncRNAs remain uncharacterized in the context of BC metabolic reprogramming, and the specific mechanisms through which they exert their effects are still poorly defined.