KCNJ10 and myeloid sarcoma: In our current study, we made an intriguing discovery that an initial impairment of Kir4.1 channels occurred in spinal cord oligodendrocyte precursor cells (OPCs) rather than in astrocytes in a mouse model of experimental autoimmune encephalomyelitis (EAE), while the levels of Kir4.1 antibodies in both EAE mouse serum and MS patient serum were significantly elevated.