We observed significant upregulation of the transcriptional levels of Ifnb1, Ifit1, Ifit2, Ifit3, Irf7, and Mx1 in irradiated 4T1 tumor tissues (Figure 1c) and irradiated CT26, H22, and GL261 carcinoma cells (Figure S1a, Supporting Information). Here, IRF7 is linked to neoplasm.