In the antitumor immune cycle triggered by RT, DCs are responsible for the uptake of tumor antigens and the activation of CD8+T cells, which migrate and infiltrate tumor tissues to specifically recognize and kill tumor cells, thereby initiating the adaptive immune response; NK cells rapidly initiate the innate immune response without antigen presentation; M1‐type macrophages coordinately attack tumors through secreting proinflammatory cytokines.[20, 58, 64]. The gene discussed is CD8A; the disease is neoplasm.