TGFB1 and neoplasm: Conversely, the down‐regulated DEGs were predominantly enriched in tumor stroma remodeling‐related pathways, such as extracellular matrix organization, collagen fibril organization, regulation of collagen metabolic process, regulation of cellular response to TGF‐beta stimulus, EMT, vasculature development, and regulation of angiogenesis, endothelial cell migration, regulation of endothelial cell proliferation, sprouting angiogenesis, VEGF signaling pathway, negative regulation of epithelial proliferation, etc (Figure 7f,h).