Previous studies have demonstrated that WTAP plays a pivotal role in m6A modification of lncRNAs, such as enhancing the stability of DIAPH1‐AS1 in nasopharyngeal carcinoma, thereby promoting tumor growth and metastasis.[18] Additionally, WTAP‐mediated m6A modification of lncRNA NORAD contributes to intervertebral disc degeneration[60] and promotes osteosarcoma progression by stabilizing FOXD2‐AS1.[61] In the context of ESCC, WTAP‐mediated alterations in m6A modification levels of PDIA3P1 were found to enhance its stability. Here, WTAP is linked to osteosarcoma.