CGAS and systemic lupus erythematosus: Overactivation of cGAS significantly contributes to the development of both autoimmune and autoinflammatory diseases, including rheumatoid arthritis (RA)(Wang et al., 2019a), AGS(Gao et al., 2015; Gray et al., 2015; Pokatayev et al., 2016), and SLE(An et al., 2017; Gao et al., 2015; Kato et al., 2018).