PTX3 and infection: A study by Li et al. [16] found that CKD patients with higher PTX3 levels had a higher risk of dying from heart disease (HR, 1.98; 95% CI, 1.28-3.05), an infection (HR, 5.26; 95% CI, 1.60-17.31), and any cause (HR, 1.92; 95% CI, 1.44-2.56).