GLIS2 and acute myeloid leukemia: More broadly, by performing single sample GSEA (ssGSEA) on the MSigDB hallmark gene sets, we found that the CBFA2T3::GLIS2 fusion positive M7 and non-M7 AML samples and to a lesser extent the CBFA2T3::GLIS2 fusion negative M7 samples shared an enrichment in inflammatory gene signatures, including “Inflammatory response” and “IL6_JAK_STAT3_signaling” (Supplemental Fig. 3D).