To this end, we compared the expression of the JAK-STAT signature genes in primary CBFA2T3::GLIS2 positive AML (n=8), versus M6-M7-AML-non-CBFA2T3::GLIS2 AML (CG- M6, CG- M7, n = 14), versus non-M6-M7-non-CBFA2T3::GLIS2 AML (CG- not M6, not M7, n=278). This evidence concerns the gene GLIS2 and acute myeloid leukemia.