Six genes were predominantly expressed in fibroblasts (LPP, FAM114A1, P4HA2, PHLDB1, LRP1, LRRC32), suggesting a role for fibroblasts in sustaining inflammation and disrupting restoration of barrier integrity as seen in a model of atopic dermatitis 71 and recent studies implicating fibroblasts in EoE pathogenesis 22,72. The gene discussed is LRRC32; the disease is atopic eczema.