,52 Additionally, CD8A, a protective gene with the highest correlation with T cells, is a promising prognostic biomarker in bladder cancer,53 calsyntenin-2 (CSTN2) has been identified as a potential biomarker for colorectal cancer,54 and dynactin subunit 2 has been identified as an oncogene in hepatocellular carcinoma.55 Here, CD8A is linked to colorectal cancer.