Clinical data within 24 h of enrollment were collected, including age, gender, comorbidities (diabetes, hypertension, hepatic insufficiency), C-reactive protein (CRP), procalcitonin (PCT), D-dimer, white blood cell count (WBC), Sequential Organ Failure Assessment (SOFA) score, Oxygenation Index (OI), Albumin (ALB), Creatinine (Cr), and Blood Urea Nitrogen (BUN). This evidence concerns the gene CRP and Hepatic failure.