SOD2 and chronic obstructive pulmonary disease: Studies have shown that RSV is associated with reducing inflammatory cell infiltration, improving the production of pro-inflammatory cytokines (TNF-α, IL-6, GM-CSF, IL-1β, and IL-8), and up-regulating antioxidant genes (SIRT1, PGC-1α, CAT, SOD1, and SOD2) in the treatment of COPD (Ma and Li, 2020; Wang et al., 2017).