MAPK8 and chronic obstructive pulmonary disease: mtROS might affect macrophage M1 polarization via MAPK, JNK/c-Jun, JNK-SOD2 and JNK-m6A-p38 signaling pathways in COPD (Feng et al., 2023; Hu et al., 2023; Liu Z. et al., 2020;).