Third, this study comprehensively evaluated multiple osteoporosis-related indicators (such as BMD, BV/TV, Tb.N, Tb.Th, and Tb.Sp), and combined the analysis of serum metabolic markers (such as CTX-1, TRAP-5b, and OCN), systematically revealing the comprehensive effects of CUR in promoting bone formation and inhibiting bone resorption. Here, BGLAP is linked to osteoporosis.