Recent studies have proposed potential associations between IL-17 and the development, severity, and treatment resistance of depressive disorders (Waisman et al. 2015; Davami et al. 2016; Nothdurfter et al. 2021); however, these findings continue to be the subject of debate (Liu et al. 2012; Kim et al. 2013). The gene discussed is IL17A; the disease is depressive disorder.