BPA also acts as an obesogenic chemical, changing early adipogenesis by modulating adipocyte hypertrophy and overexpression of lipogenic genes, including peroxisome proliferator-activated receptor gamma (PPARγ) (a nuclear receptor that acts as a master regulator of adipogenesis, which dysregulation is involved in the onset of diabetes and obesity), sterol regulatory element-binding protein 1C, lipoprotein lipase (LPL), and fatty acid synthase, leading to obesity and other metabolic dysfunctions (25). The gene discussed is PPARG; the disease is obesity due to melanocortin 4 receptor deficiency.